Index
- S- adenosyl methionine or Same: what are its properties and health benefits?
- What is the SAMe?
- What are the indications for -S- adenosyl methionine?
- How to take this product?
- Contraindications and Adverse Reactions
S- adenosyl methionine or Same: what are its properties and health benefits?
Nutrients and substances that the body needs to function better are either taken from food or manufactured and produced by the body itself. In the latter category is -S- adenosyl methionine. This is an all-natural substance made by the body. It plays an important role in the manufacture of protein molecules and hormones or antioxidants. A deficiency in this substance can therefore be harmful to health. Hence the interest of taking it as a dietary supplement.
What is the SAMe?
S- adenosyl methionine is also known by the simplified name "adenosyl methionine" or by the acronym SAMe (pronounced "sammy"). The "e" in this acronym stands for the "enteric" coating on the tablet. This coating gives the tablet a good resistance to stomach acid so that it is completely absorbed by the intestine.
SAMe plays an important role during the glutathione cycle. Glutathione is a powerful antioxidant that the body makes itself. In addition, -S- adenosyl methionine also plays an important role in the synthesis, activation and metabolism of certain proteins, DNA and RNA, neurotransmitters and hormones. To this end, it is an essential substance for health, particularly for the proper functioning of the liver and the central nervous system.
What are the indications for -S- adenosyl methionine?
Since it is a substance essential to the body for its proper functioning, a deficiency in SAMe can be problematic. Especially since certain factors promote the exhaustion of this substance. This is the case with alcohol consumption, pollution, stress or even a deficiency of zinc, magnesium and vitamins B6, B9, B12. It should also be noted that a deficiency in SAMe causes depression, cardiovascular disorders, certain types of cancer, accelerated aging, dementia, autism, fatigue or liver failure.
Taking S adenosyl methionine as a dietary supplement has proven to be the best way to compensate for these deficiencies. In fact, -S- adenosyl methionine is indicated in several cases of health problems:
- In cases of depression - various clinical studies have been conducted on the antidepressant properties of -S- adenosyl methionine. It was found that this dietary supplement is as effective as the SRI which is generally the treatment for depressed people. Moreover, in people with HIV/AIDS, taking SAMe for one week improved their moods and states.
- During joint degeneration - in 2002, the US government agency "Agency for Healthcare Research and Quality" conducted a meta-analysis of 11 clinical trials. It came out that SAMe had similar effects to traditional anti-inflammatory drugs when it came to treating joint disorders, particularly osteoarthritis. In addition, studies have shown that people with low blood levels of SAMe have a higher risk of developing osteoarthritis and other joint conditions.
- In the case of cognitive impairment - generally, cognitive impairment always accompanies depression. Because it actively participates in the synthesis of neurotransmitters, SAMe can be used to treat memory problems. All the more so as it has the property of being able to help reduce the spread of amyloid plaques, which are a characteristic sign of Alzheimer's disease.
- During cirrhosis and liver failure - the body's synthesis of SAMe takes place in the liver. When the level of S adenosyl methionine is abnormal (decreasing or increasing), the liver no longer functions properly. This is why SAMe supplementation increases the chance of survival for people with alcohol-induced cirrhosis.
- In the case of fibromyalgia - the term "fibromyalgia" includes all chronic pain in the muscles. These are often accompanied by a feeling of fatigue, the cause of which is still unknown. A supplement of SAMe can relieve the pain associated with fibromyalgia.
How to take this product?
SAMe is a food supplement that has been synthetically manufactured. Thus, it is offered in a bottle containing 30 capsules. The capsules in question have gastroresistant properties. This means that they can pass into the stomach without being destroyed by gastric juices. Generally, these capsules are dosed at 200 mg.
The indicated dosage for this dietary supplement is 1 capsule per day. It is also preferable to take this capsule on an empty stomach, as this is when it is easily absorbed by the body.
Contraindications and Adverse Reactions
Although SAMe is a product that the body needs for its proper functioning, it is essential to respect the dosage indicated on the bottle. In terms of adverse reactions, no serious problems have been observed when the dosage does not exceed 1200 mg per day. However, it is recommended to take this dietary supplement only if the doctor's opinion is favourable. In fact, certain contraindications exist for -S- adenosyl methionine.
For example, it should not be used by people with bipolar disorder. Also, caution should be exercised when you are on antidepressants and taking them. Indeed, their interaction can cause anxiety and tachycardia.
