Index
- The unsuspected virtues of berberine
- What is berberine?
- How does it affect the body?
- The benefits of berberine on the body
- Its actions in relation to cardiovascular disorders
- Berberine in the treatment of diabetes
- The effects of berberine on cognitive function
- Berberine and overweight
- The actions of berberine on metabolism
- Contraindications and Adverse Reactions
The unsuspected virtues of berberine
Berberine has long been used in Chinese medicine and is classified as one of the most powerful natural substances available. It is usually taken as a dietary supplement and has many benefits for the body. In fact, although it is particularly indicated for type 2 diabetics because it helps regulate sugar metabolism, it also acts on many body functions. Find out below what the main benefits of using berberine are.
What is berberine?
In the Chinese pharmacopoeia, berberine has been used for more than 2500 years. In fact, it appears in the very first book of Chinese medicine relating to herbal medicine "Shennong Ben Cao Jing" which was written 200 years before our era. Berberine is above all an alkaloid. This plant compound is distinguished by the presence of at least one nitrogen atom. For this purpose, it can be found in certain botanical families such as renunculaceae, berberidaceae, menispermaceae or papaveraceae. But even though these plants are widely distributed throughout the world, berberine is particularly effective when taken as a dietary supplement, in the form of a tablet or capsule.
How does it affect the body?
The main action of berberine on the body is the activation of AMPK or Adenosine Mono- Phosphate Kinase. The latter is an enzyme necessary for the energy balance in all cells. The activation of AMPK then has the following effect:
- Stimulation of liver fatty acid oxidation
- Inhibition of lipogenesis and cholesterol synthesis
- Stimulation of glucose absorption by the muscles
- Stimulation of the oxidation of fatty acids
This alkaloid also has hypoglycemic effects, making it a very interesting dietary supplement for treating type 2 diabetes. In addition to this, berberine also acts on the regulation of fat storage in the body, reducing the risks associated with brain degeneration while providing effective protection for the intestinal wall.
The berberine molecule is also highly valued for its anti-inflammatory and antifungal effects.
The benefits of berberine on the body
Many therapeutic virtues are attributed to this alkaloid. In fact, because of its many effects, berberine can be used to treat a variety of health problems. In fact, it is a natural treatment accessible to all.
Its actions in relation to cardiovascular disorders
By participating in the inhibition of the synthesis of fatty acids, the berberine molecule helps to reduce the level of circulating lipids in the body. In simpler terms, this product helps to reduce the level of bad cholesterol. Also, berberine works by reducing fatty deposits that can form throughout the body. This promotes blood circulation while maintaining cardiovascular health. Moreover, it is well known that berberine is an effective vasodilator whose function is to reduce blood pressure and improve heart function.
Berberine in the treatment of diabetes
The blood sugar regulating action of berberine makes it particularly interesting in the treatment and prevention of type 2 diabetes. This is mainly due to the hypoglycemic effect of this molecule. By reducing the level of glucose in the blood, it helps prevent or mitigate the effects of hyperglycemia on health.
In addition, it has also been proven that this food supplement acts on cells by increasing their sensitivity to insulin. The activity of insulin is thus optimized and its production by the beta cells of the pancreas is stabilized.
The effects of berberine on cognitive function
Berberine has a neuroprotective effect. It thus helps to maintain cognitive functions, particularly memory. At the same time, berberine also promotes mood balance and reduces the risk of nerve degeneration, which is the cause of many age-related diseases (such as Alzheimer's or Parkinson's).
Berberine and overweight
By acting against bad fats and avoiding their storage, berberine is an excellent slimming ally. In addition to this, its favourable effect on the metabolism is one of the key elements in the fight against overweight.
The actions of berberine on metabolism
This alkaloid is also formidable for fighting the bacteria that cause gastric disorders. Its action consists in preventing the release of toxin by these bacteria, and this is made possible by its anti-inflammatory properties. The berberine molecule acts by modifying the composition of the intestinal flora so as to favour good bacteria. It is therefore particularly indicated for people suffering from irritable bowel syndrome.
Contraindications and Adverse Reactions
Berberine can be taken in tablet, capsule or powder form. When taken at the right dosage, no side effects occur. However, in very rare cases, mild disorders such as bloating or constipation have been noted. In any case, it should be noted that this product is not suitable for pregnant women and young children. Therefore, you should always seek the advice of your doctor before taking it.
References
- Bruno Lacroix, Metabolic alterations (dysglycemias and dyslipidemias): La Berberine " Une alternative aux traitements pharmacologiques ", in: La lettre, Institut Européen de Physionutrition et de Phytothérapie, n° 32, 16 pages. https://iepp-eu.com/wp- content/uploads/2013/04/Lettre-IEPP-n32-berberine.pdf
- Hui Dong et al., Berberine in the Treatment of Type 2 Diabetes Mellitus : A systemic Review and Meta-Analysis, Octobre 2012, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478874/


